Name | 2,5-Dibromobenzenesulfonyl chloride |
Synonyms | 2,5-DIBROMOBENZENESU 5-DibroMobenzenesulfonyl chloride 2,5-DIBROMOBENZENESULFONYL CHLORIDE 2,5-Dibromobenzenesulfonyl chloride 2,5-Dibromobenzenesulphonyl chloride 2,5-DIBROMOBENZENESULPHONYL CHLORIDE Benzenesulfonyl chloride, 2,5-dibromo- |
CAS | 23886-64-8 |
EINECS | 623-873-5 |
InChI | InChI=1/C6H3Br2ClO2S/c7-4-1-2-5(8)6(3-4)12(9,10)11/h1-3H |
Molecular Formula | C6H3Br2ClO2S |
Molar Mass | 334.41 |
Density | 2?+-.0.06 g/cm3(Predicted) |
Melting Point | 69-73 °C (lit.) |
Boling Point | 133°C 1mm |
Flash Point | 174.2°C |
Vapor Presure | 3.53E-05mmHg at 25°C |
BRN | 2694054 |
Storage Condition | Inert atmosphere,Room Temperature |
Sensitive | Moisture Sensitive |
Refractive Index | 1.622 |
Hazard Symbols | C - Corrosive |
Risk Codes | 34 - Causes burns |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 3 |
Hazard Note | Corrosive/Moisture Sensitive |
Hazard Class | 8 |
Packing Group | II |
introduction | 2,5-dibromobenzenesulfonyl chloride is a derivative of bromobenzenesulfonyl chloride, which has been widely used as an important organic intermediate. In addition to being used to synthesize bioactive insecticides, it is increasingly showing its potential application value in the field of new drug research, which can be used to synthesize angiotensin receptor antagonists, synthesize endothelin receptor antagonists, etc. |
Preparation | 2,5-dibromobenzenesulfonyl chloride can be made of bromothiophenol as raw material, condensed with chloromethyl methyl ether, and oxidized and chlorinated by chlorine. The synthesis roadmap is as follows: |